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Splicing Kinase SRPK1 Conforms to the Landscape of Its SR Protein Substrate()

The splicing function of SR proteins is regulated by multisite phosphorylation of their C-terminal RS (arginine-serine rich) domains. SRPK1 has been shown to phosphorylate the prototype SR protein SRSF1 using a directional mechanism in which eleven serines flanked by arginines are sequentially feed...

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Detalhes bibliográficos
Main Authors: Aubol, Brandon E., Jamros, Michael, McGlone, Maria L., Adams, Joseph A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865722/
https://ncbi.nlm.nih.gov/pubmed/24074032
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi4010864
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