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Activation of Adenylate Cyclase by Heat-Labile Escherichia Coli Enterotoxin

Highly purified, polymyxin-released, low molecular weight Escherichia coli heat-labile enterotoxin (LT) catalyzed the hydrolysis of NAD to ADP-ribose and nicotinamide. This NAD glycohydrolase activity was stimulated by dithiothreitol and was independent of cellular components. Nicotinamide formation...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Moss, Joel, Richardson, Stephen H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1978
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC371764/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/209060/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI109127
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