Effects of Site-Directed Mutagenesis of Escherichia coli Heat-Labile Enterotoxin on ADP-Ribosyltransferase Activity and Interaction with ADP-Ribosylation Factors

Escherichia coli heat-labile enterotoxin (LT), an oligomeric protein with one A subunit (LTA) and five B subunits, exerts its effects via the ADP-ribosylation of G(sα), a guanine nucleotide-binding (G) protein that activates adenylyl cyclase. LTA also ADP-ribosylates simple guanidino compounds (e.g....

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Bibliografski detalji
Glavni autori: A. Stevens, Linda, Moss, Joel, Vaughan, Martha, Pizza, Mariagrazia, Rappuoli, Rino
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Molecular and Cellular Pathogenesis
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC96305/
https://ncbi.nlm.nih.gov/pubmed/9864224
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