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Activation of Adenylate Cyclase by Heat-Labile Escherichia Coli Enterotoxin: EVIDENCE FOR ADP-RIBOSYLTRANSFERASE ACTIVITY SIMILAR TO THAT OF CHOLERAGEN
Highly purified, polymyxin-released, low molecular weight Escherichia coli heat-labile enterotoxin (LT) catalyzed the hydrolysis of NAD to ADP-ribose and nicotinamide. This NAD glycohydrolase activity was stimulated by dithiothreitol and was independent of cellular components. Nicotinamide formation...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
1978
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC371764/ https://ncbi.nlm.nih.gov/pubmed/209060 |
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