Activation of Adenylate Cyclase by Heat-Labile Escherichia Coli Enterotoxin: EVIDENCE FOR ADP-RIBOSYLTRANSFERASE ACTIVITY SIMILAR TO THAT OF CHOLERAGEN

Highly purified, polymyxin-released, low molecular weight Escherichia coli heat-labile enterotoxin (LT) catalyzed the hydrolysis of NAD to ADP-ribose and nicotinamide. This NAD glycohydrolase activity was stimulated by dithiothreitol and was independent of cellular components. Nicotinamide formation...

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Main Authors: Moss, Joel, Richardson, Stephen H.
Format: Artigo
Jezik:Inglês
Izdano: 1978
Teme:
Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC371764/
https://ncbi.nlm.nih.gov/pubmed/209060
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