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Promoting natural killer cell functions by recombinant immunoligands mimicking an induced self phenotype
Immunoligands for stimulatory natural killer (NK)-cell receptors can be targeted to the surface of malignant cells by fusing them to antibody fragments. Mimicking an “induced-self” phenotype, such recombinant immunoligands signal danger, trigger NK-cell cytotoxicity and synergistically enhance antib...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3716743/ https://ncbi.nlm.nih.gov/pubmed/23894708 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.24481 |
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