Enhancing natural killer cell-mediated lysis of lymphoma cells by combining therapeutic antibodies with CD20-specific immunoligands engaging NKG2D or NKp30

Antibody-dependent cell-mediated cytotoxicity (ADCC) mediated through the IgG Fc receptor FcγRIIIa represents a major effector function of many therapeutic antibodies. In an attempt to further enhance natural killer (NK) cell-mediated ADCC, we combined therapeutic antibodies against CD20 and CD38 wi...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Oncoimmunology
Glavni autori: Kellner, Christian, Günther, Andreas, Humpe, Andreas, Repp, Roland, Klausz, Katja, Derer, Stefanie, Valerius, Thomas, Ritgen, Matthias, Brüggemann, Monika, van de Winkel, Jan GJ, Parren, Paul WHI, Kneba, Michael, Gramatzki, Martin, Peipp, Matthias
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2015
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760288/
https://ncbi.nlm.nih.gov/pubmed/26942070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1058459
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items