Tribody [(HER2)(2)xCD16] Is More Effective Than Trastuzumab in Enhancing γδ T Cell and Natural Killer Cell Cytotoxicity Against HER2-Expressing Cancer Cells

An enhanced expression of human epidermal growth factor receptor 2 (HER2, ErbB2) often occurs in an advanced stage of breast, ovarian, gastric or esophageal cancer, and pancreatic ductal adenocarcinoma (PDAC). Commonly, HER2 expression is associated with poor clinical outcome or chemoresistance in o...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Oberg, Hans H., Kellner, Christian, Gonnermann, Daniel, Sebens, Susanne, Bauerschlag, Dirk, Gramatzki, Martin, Kabelitz, Dieter, Peipp, Matthias, Wesch, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5916959/
https://ncbi.nlm.nih.gov/pubmed/29725336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.00814
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