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Phenotype and regulation of immunosuppressive Vδ2-expressing γδ T cells
The proliferation and interleukin-2 production of CD4(+)CD25(−) αβ T cells were inhibited in a cell-contact manner by Vδ2 γδ T cells. The transcription factor Helios was constitutively expressed in about one-third of circulating γδ T cells and was upregulated by CD28-signaling. Our data suggest that...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Springer Basel
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3997799/ https://ncbi.nlm.nih.gov/pubmed/24091816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1467-1 |
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