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Phenotype and regulation of immunosuppressive Vδ2-expressing γδ T cells

The proliferation and interleukin-2 production of CD4(+)CD25(−) αβ T cells were inhibited in a cell-contact manner by Vδ2 γδ T cells. The transcription factor Helios was constitutively expressed in about one-third of circulating γδ T cells and was upregulated by CD28-signaling. Our data suggest that...

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Détails bibliographiques
Auteurs principaux: Peters, Christian, Oberg, Hans-Heinrich, Kabelitz, Dieter, Wesch, Daniela
Format: Artigo
Langue:Inglês
Publié: Springer Basel 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3997799/
https://ncbi.nlm.nih.gov/pubmed/24091816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-013-1467-1
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