Galectin-3 Released by Pancreatic Ductal Adenocarcinoma Suppresses γδ T Cell Proliferation but Not Their Cytotoxicity

Pancreatic ductal adenocarcinoma (PDAC) is characterized by an immunosuppressive tumor microenvironment with a dense desmoplastic stroma. The expression of β-galactoside-binding protein galectin-3 is regarded as an intrinsic tumor escape mechanism for inhibition of tumor-infiltrating T cell function...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Front Immunol
Päätekijät: Gonnermann, Daniel, Oberg, Hans-Heinrich, Lettau, Marcus, Peipp, Matthias, Bauerschlag, Dirk, Sebens, Susanne, Kabelitz, Dieter, Wesch, Daniela
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2020
Aiheet:
Immunology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7338555/
https://ncbi.nlm.nih.gov/pubmed/32695112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.01328
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