Perspectives of Fc engineered antibodies in CD19 targeting immunotherapies in pediatric B-cell precursor acute lymphoblastic leukemia

CD19 immunotherapies based on T cells opened new avenues in the treatment of pediatric B-cell precursor acute lymphoblastic leukemia (BCP-ALL). However, Fc engineered CD19 antibodies may also bear great potential. In light of recent preclinical and clinical data, perspectives of such antibodies desi...

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Bibliografiske detaljer
Udgivet i:Oncoimmunology
Main Authors: Kellner, Christian, Peipp, Matthias, Gramatzki, Martin, Schrappe, Martin, Schewe, Denis M.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6136853/
https://ncbi.nlm.nih.gov/pubmed/30221037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1448331
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