Identification and Characterization of a Novel HIV-1 Nucleotide-Competing Reverse Transcriptase Inhibitor Series

Several groups have recently reported on the identification of nucleotide-competing reverse transcriptase inhibitors (NcRTIs), a new class of RT inhibitors. NcRTIs reversibly inhibit binding of the incoming nucleotide to the RT active site but do not act as chain terminators, unlike the nucleos(t)id...

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Hlavní autoři: Rajotte, D., Tremblay, S., Pelletier, A., Salois, P., Bourgon, L., Coulombe, R., Mason, S., Lamorte, L., Sturino, C. F., Bethell, R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2013
Témata:
Antiviral Agents
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716156/
https://ncbi.nlm.nih.gov/pubmed/23545531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00113-13
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