Pharmacokinetics-Pharmacodynamics of Tazobactam in Combination with Ceftolozane in an In Vitro Infection Model

Despite β-lactamase inhibitors being available for clinical use for nearly 30 years, a paucity of data exists describing the pharmacokinetic-pharmacodynamic (PK-PD) determinants of efficacy for these agents. Herein, we describe dose fractionation studies designed to determine the exposure measure mo...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: VanScoy, Brian, Mendes, Rodrigo E., Nicasio, Anthony M., Castanheira, Mariana, Bulik, Catharine C., Okusanya, Olanrewaju O., Bhavnani, Sujata M., Forrest, Alan, Jones, Ronald N., Friedrich, Lawrence V., Steenbergen, Judith N., Ambrose, Paul G.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2013
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3716129/
https://ncbi.nlm.nih.gov/pubmed/23629705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02513-12
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk