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Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles
The protease β-secretase 1 (Bace1) was identified through its critical role in production of amyloid-β peptides (Aβ), the major component of amyloid plaques in Alzheimer’s disease. Bace1 is considered a promising target for the treatment of this pathology, but processes additional substrates, among...
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| 主要な著者: | , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
European Molecular Biology Organization
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3715864/ https://ncbi.nlm.nih.gov/pubmed/23792428 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.146 |
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