Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells

Cholesterol is a major constituent of myelin membranes, which insulate axons and allow saltatory conduction. Therefore, Schwann cells, the myelinating glia of the peripheral nervous system, need to produce large amounts of cholesterol. Here, we define a crucial role of the transcription factor Maf i...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Kim, Minchul, Wende, Hagen, Walcher, Jan, Kühnemund, Johannes, Cheret, Cyril, Kempa, Stefan, McShane, Erik, Selbach, Matthias, Lewin, Gary R., Birchmeier, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004071/
https://ncbi.nlm.nih.gov/pubmed/29748249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.310490.117
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