Maf links Neuregulin1 signaling to cholesterol synthesis in myelinating Schwann cells

Cholesterol is a major constituent of myelin membranes, which insulate axons and allow saltatory conduction. Therefore, Schwann cells, the myelinating glia of the peripheral nervous system, need to produce large amounts of cholesterol. Here, we define a crucial role of the transcription factor Maf i...

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Publicat a:Genes Dev
Autors principals: Kim, Minchul, Wende, Hagen, Walcher, Jan, Kühnemund, Johannes, Cheret, Cyril, Kempa, Stefan, McShane, Erik, Selbach, Matthias, Lewin, Gary R., Birchmeier, Carmen
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2018
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004071/
https://ncbi.nlm.nih.gov/pubmed/29748249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.310490.117
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