Activation of MAPK overrides the termination of myelin growth and replaces Nrg1/ErbB3 signals during Schwann cell development and myelination

Myelination depends on the synthesis of large amounts of myelin transcripts and proteins and is controlled by Nrg1/ErbB/Shp2 signaling. We developed a novel pulse labeling strategy based on stable isotope labeling with amino acids in cell culture (SILAC) to measure the dynamics of myelin protein pro...

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Detalhes bibliográficos
Main Authors: Sheean, Maria E., McShane, Erik, Cheret, Cyril, Walcher, Jan, Müller, Thomas, Wulf-Goldenberg, Annika, Hoelper, Soraya, Garratt, Alistair N., Krüger, Markus, Rajewsky, Klaus, Meijer, Dies, Birchmeier, Walter, Lewin, Gary R., Selbach, Matthias, Birchmeier, Carmen
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3923970/
https://ncbi.nlm.nih.gov/pubmed/24493648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.230045.113
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