The tyrosine phosphatase Shp2 (PTPN11) directs Neuregulin-1/ErbB signaling throughout Schwann cell development

The nonreceptor tyrosine phosphatase Shp2 (PTPN11) has been implicated in tyrosine kinase, cytokine, and integrin receptor signaling. We show here that conditional mutation of Shp2 in neural crest cells and in myelinating Schwann cells resulted in deficits in glial development that are remarkably si...

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Detalles Bibliográficos
Autores principales: Grossmann, Katja S., Wende, Hagen, Paul, Florian E., Cheret, Cyril, Garratt, Alistair N., Zurborg, Sandra, Feinberg, Konstantin, Besser, Daniel, Schulz, Herbert, Peles, Elior, Selbach, Matthias, Birchmeier, Walter, Birchmeier, Carmen
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2742405/
https://ncbi.nlm.nih.gov/pubmed/19805360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904336106
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