The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system

Neuregulins (NDF, heregulin, GGF ARIA, or SMDF) are EGF-like growth and differentiation factors that signal through tyrosine kinase receptors of the ErbB family. Here, we report a novel phenotype in mice with targeted mutations in the erbB2, erbB3, or neuregulin-1 genes. These three mutations cause...

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Autores principales: Britsch, Stefan, Li, Li, Kirchhoff, Susanne, Theuring, Franz, Brinkmann, Volker, Birchmeier, Carmen, Riethmacher, Dieter
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1998
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC316903/
https://ncbi.nlm.nih.gov/pubmed/9637684
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