Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles

The protease β-secretase 1 (Bace1) was identified through its critical role in production of amyloid-β peptides (Aβ), the major component of amyloid plaques in Alzheimer’s disease. Bace1 is considered a promising target for the treatment of this pathology, but processes additional substrates, among...

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Bibliographische Detailangaben
Hauptverfasser: Cheret, Cyril, Willem, Michael, Fricker, Florence R, Wende, Hagen, Wulf-Goldenberg, Annika, Tahirovic, Sabina, Nave, Klaus-Armin, Saftig, Paul, Haass, Christian, Garratt, Alistair N, Bennett, David L, Birchmeier, Carmen
Format: Artigo
Sprache:Inglês
Veröffentlicht: European Molecular Biology Organization 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715864/
https://ncbi.nlm.nih.gov/pubmed/23792428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2013.146
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