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Development of M(1) mAChR Allosteric and Bitopic Ligands: Prospective Therapeutics for the Treatment of Cognitive Deficits

[Image: see text] Since the cholinergic hypothesis of memory dysfunction was first reported, extensive research efforts have focused on elucidating the mechanisms by which this intricate system contributes to the regulation of processes such as learning, memory, and higher executive function. Severa...

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Autors principals: Davie, Briana J., Christopoulos, Arthur, Scammells, Peter J.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2013
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3715844/
https://ncbi.nlm.nih.gov/pubmed/23659787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn400086m
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