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Nucleophilic addition to silyl-protected five-membered ring oxocarbenium ions governed by stereoelectronic effects

A series of fused-bicyclic acetals containing a disiloxane ring was investigated to evaluate the source of selectivity in silyl-protected 2-deoxyribose systems. The disiloxane ring unexpectedly enables the diaxial conformer of the cation to be stabilized by an electronegative atom at C-3. This low e...

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Hlavní autoři: Tran, Vi Tuong, Woerpel, K. A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3713616/
https://ncbi.nlm.nih.gov/pubmed/23738497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo400945j
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