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Mice overexpressing wild-type human alpha-synuclein display alterations in colonic myenteric ganglia and defecation
BACKGROUND: Prevalent non-motor symptoms of Parkinson’s disease (PD) include gastrointestinal motor impairments and advanced stage PD displays pathological aggregates of α-synuclein in colonic enteric neurons. We previously showed that 12 months old mice overexpressing human wild type α-synuclein un...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712640/ https://ncbi.nlm.nih.gov/pubmed/22779732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2012.01974.x |
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