Colonic inflammation affects myenteric alpha-synuclein in nonhuman primates

Background: Parkinson’s disease (PD) patients frequently present gastrointestinal (GI) dysfunction that, in many cases, predates the onset of motor symptoms. In PD, the presynaptic protein alpha-synuclein (α-syn) undergoes pathological changes, including phosphorylation and aggregation leading to th...

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Detalhes bibliográficos
Publicado no:J Inflamm Res
Main Authors: Resnikoff, Henry, Metzger, Jeanette M, Lopez, Mary, Bondarenko, Viktoriya, Mejia, Andres, Simmons, Heather A, Emborg, Marina E
Formato: Artigo
Idioma:Inglês
Publicado em: Dove 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6511240/
https://ncbi.nlm.nih.gov/pubmed/31123415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S196552
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