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Mice overexpressing wild-type human alpha-synuclein display alterations in colonic myenteric ganglia and defecation

BACKGROUND: Prevalent non-motor symptoms of Parkinson’s disease (PD) include gastrointestinal motor impairments and advanced stage PD displays pathological aggregates of α-synuclein in colonic enteric neurons. We previously showed that 12 months old mice overexpressing human wild type α-synuclein un...

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Bibliografski detalji
Glavni autori: WANG, L., MAGEN, I., YUAN, P-Q, SUBRAMANIAM, S. R., RICHTER, F., CHESSELET, M-F, TACHÉ, Y.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712640/
https://ncbi.nlm.nih.gov/pubmed/22779732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2982.2012.01974.x
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