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Region specific mitochondrial impairment in mice with widespread overexpression of alpha-synuclein

Parkinson’s disease (PD) is characterized by the progressive degeneration of nigrostriatal dopaminergic neurons leading to motor deficits. The mechanisms underlying the preferential vulnerability of nigrostriatal dopaminergic neurons in PD remain poorly understood. Recent evidence supports a role fo...

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Detalhes bibliográficos
Main Authors: SUBRAMANIAM, Sudhakar Raja, VERGNES, Laurent, FRANICH, Nicholas R., REUE, Karen, CHESSELET, Marie-Francoise
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4205109/
https://ncbi.nlm.nih.gov/pubmed/25016198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2014.06.017
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