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Receptors, Endocytosis, and Trafficking: the Biological Basis of Targeted Delivery of Antisense and siRNA Oligonucleotides
The problem of targeted delivery of antisense and siRNA oligonucleotides can be resolved into two distinct aspects. The first concerns devising ligand-oligonucleotide or ligand-carrier moieties that bind with high selectivity to receptors on the cell type of interest and that are efficiently interna...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3712333/ https://ncbi.nlm.nih.gov/pubmed/23163768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/1061186X.2012.740674 |
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