Cargando...

The Biological Effect of an Antisense Oligonucleotide Depends on Its Route of Endocytosis and Trafficking

We demonstrate that the biological effect of an oligonucleotide is influenced by its route of cellular uptake. Utilizing a splice-switching antisense oligonucleotide (SSO) and a sensitive reporter assay involving correction of RNA splicing, we examined induction of luciferase in cells treated either...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Alam, Md. Rowshon, Ming, Xin, Dixit, Vidula, Fisher, Michael, Chen, Xiaoyuan, Juliano, Rudolph L.
Formato: Artigo
Idioma:Inglês
Publicado: Mary Ann Liebert, Inc. 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883474/
https://ncbi.nlm.nih.gov/pubmed/20038250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/oli.2009.0211
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!