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Negative Cooperativity in the EGF Receptor
Scatchard analyses of the binding of EGF to its receptor yield concave up Scatchard plots, indicative of some type of heterogenity in ligand binding affinity. This was typically interpreted as being due to the presence of two independent binding site–one of high affinity representing ≤10% of the rec...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711752/ https://ncbi.nlm.nih.gov/pubmed/22260659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20110610 |
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