A carregar...
The Tethering Arm of the EGF Receptor Is Required for Negative Cooperativity and Signal Transduction
The EGF receptor is a classical receptor-tyrosine kinase. In the absence of ligand, the receptor adopts a closed conformation in which the dimerization arm of subdomain II interacts with the tethering arm in subdomain IV. Following the binding of EGF, the receptor opens to form a symmetric, back-to-...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3020763/ https://ncbi.nlm.nih.gov/pubmed/21047778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.182899 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|