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The RFC Clamp Loader: Structure and Function
The eukaryotic RFC clamp loader couples the energy of ATP hydrolysis to open and close the circular PCNA sliding clamp onto primed sites for use by DNA polymerases and repair factors. Structural studies reveal clamp loaders to be heteropentamers. Each subunit contains a region of homology to AAA+ pr...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3711244/ https://ncbi.nlm.nih.gov/pubmed/22918590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-94-007-4572-8_14 |
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