Akt and mTOR pathways differentially regulate the development of natural and inducible T(H)17 cells

Natural T helper 17 (nT(H)17) cells are a population of interleukin 17 (IL-17)-producing cells that acquire effector function in the thymus during development. Here we demonstrate that the serine/threonine kinase Akt plays a critical role in regulating nT(H)17 cell development. While Akt and the dow...

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Bibliografiset tiedot
Päätekijät: Kim, Jiyeon S., Sklarz, Tammarah, Banks, Lauren, Gohil, Mercy, Waickman, Adam T., Skuli, Nicolas, Krock, Bryan L., Luo, Chong T., Hu, Weihong, Pollizzi, Kristin N., Li, Ming O., Rathmell, Jeffrey C., Birnbaum, Morris J., Powell, Jonathan D., Jordan, Martha S., Koretzky, Gary A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2013
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711189/
https://ncbi.nlm.nih.gov/pubmed/23644504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2607
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