Akt and mTOR pathways differentially regulate the development of natural and inducible T(H)17 cells

Natural T helper 17 (nT(H)17) cells are a population of interleukin 17 (IL-17)-producing cells that acquire effector function in the thymus during development. Here we demonstrate that the serine/threonine kinase Akt plays a critical role in regulating nT(H)17 cell development. While Akt and the dow...

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Detalhes bibliográficos
Main Authors: Kim, Jiyeon S., Sklarz, Tammarah, Banks, Lauren, Gohil, Mercy, Waickman, Adam T., Skuli, Nicolas, Krock, Bryan L., Luo, Chong T., Hu, Weihong, Pollizzi, Kristin N., Li, Ming O., Rathmell, Jeffrey C., Birnbaum, Morris J., Powell, Jonathan D., Jordan, Martha S., Koretzky, Gary A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3711189/
https://ncbi.nlm.nih.gov/pubmed/23644504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2607
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