Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

Class I histone deacetylases (HDAC1, HDAC2, and HDAC3) are recruited by cognate corepressor proteins into specific transcriptional repression complexes that target HDAC activity to chromatin resulting in chromatin condensation and transcriptional silencing. We previously reported the structure of HD...

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Détails bibliographiques
Auteurs principaux: Millard, Christopher J., Watson, Peter J., Celardo, Ivana, Gordiyenko, Yuliya, Cowley, Shaun M., Robinson, Carol V., Fairall, Louise, Schwabe, John W.R.
Format: Artigo
Langue:Inglês
Publié: Cell Press 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710971/
https://ncbi.nlm.nih.gov/pubmed/23791785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.05.020
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