Class I HDACs Share a Common Mechanism of Regulation by Inositol Phosphates

Class I histone deacetylases (HDAC1, HDAC2, and HDAC3) are recruited by cognate corepressor proteins into specific transcriptional repression complexes that target HDAC activity to chromatin resulting in chromatin condensation and transcriptional silencing. We previously reported the structure of HD...

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Detalhes bibliográficos
Main Authors: Millard, Christopher J., Watson, Peter J., Celardo, Ivana, Gordiyenko, Yuliya, Cowley, Shaun M., Robinson, Carol V., Fairall, Louise, Schwabe, John W.R.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710971/
https://ncbi.nlm.nih.gov/pubmed/23791785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.05.020
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