Bach2 represses effector programmes to stabilize T(reg)-mediated immune homeostasis

Through their functional diversification, distinct lineages of CD4(+) T cells play key roles in either driving or constraining immune-mediated pathology. Transcription factors are critical in the generation of cellular diversity, and negative regulators antagonistic to alternate fates often act in c...

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Autores principales: Roychoudhuri, Rahul, Hirahara, Kiyoshi, Mousavi, Kambiz, Clever, David, Klebanoff, Christopher A., Bonelli, Michael, Sciume, Giuseppe, Zare, Hossein, Vahedi, Golnaz, Dema, Barbara, Yu, Zhiya, Liu, Hui, Takahashi, Hayato, Rao, Mahadev, Muranski, Pawel, Crompton, Joseph G., Punkosdy, George, Bedognetti, Davide, Wang, Ena, Hoffmann, Victoria, Rivera, Juan, Marincola, Francesco M., Nakamura, Atsushi, Sartorelli, Vittorio, Kanno, Yuka, Gattinoni, Luca, Muto, Akihiko, Igarashi, Kazuhiko, O’Shea, John J., Restifo, Nicholas P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710737/
https://ncbi.nlm.nih.gov/pubmed/23728300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12199
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