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Studies of the Metabotropic Glutamate Receptor 5 Radioligand [(11)C]ABP688 with N-acetylcysteine Challenge in Rhesus Monkeys

Detecting changes in receptor binding at the metabotropic glutamate receptor 5 (mGluR5) with the PET allosteric antagonist, [(11)C]ABP688, may be valuable for studying dysfunctional glutamate transmission associated with psychiatric illnesses. This study was designed to validate the findings of a re...

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Autors principals: Sandiego, Christine M., Nabulsi, Nabeel, Lin, Shu-fei, Labaree, David, Najafzadeh, Soheila, Huang, Yiyun, Cosgrove, Kelly, Carson, Richard E.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3710146/
https://ncbi.nlm.nih.gov/pubmed/23424090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/syn.21656
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