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T-Bet Plays a Key Role in NK-Mediated Control of Melanoma Metastatic Disease()
Antitumor responses depend on type 1 immunity, which is severely impaired in mice deficient for the T-box expressed in T cells (T-bet) transcription factor. Both T-bet-deficient (T-bet(–/–)) NK and CTL show defective function, which can be overcome by strong stimuli due to the expression of eomesode...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3709580/ https://ncbi.nlm.nih.gov/pubmed/18523263 |
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