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T-Bet Plays a Key Role in NK-Mediated Control of Melanoma Metastatic Disease()

Antitumor responses depend on type 1 immunity, which is severely impaired in mice deficient for the T-box expressed in T cells (T-bet) transcription factor. Both T-bet-deficient (T-bet(–/–)) NK and CTL show defective function, which can be overcome by strong stimuli due to the expression of eomesode...

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Bibliografische gegevens
Hoofdauteurs: Werneck, Miriam B. F., Lugo-Villarino, Geanncarlo, Hwang, Eun Sook, Cantor, Harvey, Glimcher, Laurie H.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2008
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3709580/
https://ncbi.nlm.nih.gov/pubmed/18523263
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