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IL-2 production in developing Th1 cells is regulated by heterodimerization of RelA and T-bet and requires T-bet serine residue 508

Interleukin (IL)-2 is the predominant cytokine that is produced by naive Th cells in a primary response. It is required for proliferation and differentiation of Th precursor cells into effector cells. Initial high-level IL-2 production is followed by its decline, and the concomitant induction of cyt...

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Detalhes bibliográficos
Main Authors: Hwang, Eun Sook, Hong, Jeong-Ho, Glimcher, Laurie H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2213245/
https://ncbi.nlm.nih.gov/pubmed/16275766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20051044
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