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T-bet is required for optimal production of IFN-γ and antigen-specific T cell activation by dendritic cells
IFN-γ is well known as the signature cytokine of CD4(+) T helper 1, CD8(+), and natural killer cells, but recent studies demonstrate that antigen-presenting cells, in particular dendritic cells (DCs), are another potent source for this proinflammatory cytokine. T-bet, a transcription factor that con...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC164659/ https://ncbi.nlm.nih.gov/pubmed/12802010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1332767100 |
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