Communicable ulcerative colitis induced by T-bet deficiency in the innate immune system

Inflammatory bowel disease (IBD) has been attributed to over-exuberant host immunity or the emergence of harmful intestinal flora. The transcription factor T-bet orchestrates inflammatory genetic programs in both adaptive and innate immunity. We describe a profound and unexpected function for T-bet...

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Bibliographische Detailangaben
Hauptverfasser: Garrett, Wendy S., Lord, Graham M., Punit, Shivesh, Lugo-Villarino, Geanncarlo, Mazmanian, Sarkis, Ito, Susumu, Glickman, Jonathan N., Glimcher, Laurie H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169385/
https://ncbi.nlm.nih.gov/pubmed/17923086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.08.017
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