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Mechanism of the postreceptor defect in insulin action in human obesity. Decrease in glucose transport system activity.

We have studied insulin-stimulated 3-O-methyl glucose transport by isolated adipocytes prepared from 10 normal and 11 obese individuals. The results demonstrated that the insulin-glucose transport dose-response curves were shifted to the right in cells from the obese patients, and that the magnitude...

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Bibliografiske detaljer
Main Authors: Ciaraldi, T P, Kolterman, O G, Olefsky, J M
Format: Artigo
Sprog:Inglês
Udgivet: 1981
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC370874/
https://ncbi.nlm.nih.gov/pubmed/7026616
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