Deficiency of liver Comparative Gene Identification-58 causes steatohepatitis and fibrosis in mice

Triglyceride (TG) accumulation in hepatocytes (hepatic steatosis) preludes the development of advanced nonalcoholic fatty liver diseases (NAFLDs) such as steatohepatitis, fibrosis, and cirrhosis. Mutations in human Comparative Gene Identification-58 (CGI-58) cause cytosolic TG-rich lipid droplets to...

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Bibliografische gegevens
Hoofdauteurs: Guo, Feng, Ma, Yinyan, Kadegowda, Anil K. G., Betters, Jenna L., Xie, Ping, Liu, George, Liu, Xiuli, Miao, Hongming, Ou, Juanjuan, Su, Xiong, Zheng, Zhenlin, Xue, Bingzhong, Shi, Hang, Yu, Liqing
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Biochemistry and Molecular Biology 2013
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Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3708361/
https://ncbi.nlm.nih.gov/pubmed/23733885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M035519
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