Loss of Abhd5 Promotes Colorectal Tumor Development and Progression by Inducing Aerobic Glycolysis and Epithelial-Mesenchymal Transition

How cancer cells shift metabolism to aerobic glycolysis is largely unknown. Here we show that deficiency of α/β-hydrolase domain-containing-5 (Abhd5), an intracellular lipolytic activator that is also known as comparative gene identification-58 (CGI-58), promotes this metabolic shift and enhances ma...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ou, Juanjuan, Miao, Hongming, Ma, Yinyan, Guo, Feng, Deng, Jia, Wei, Xing, Zhou, Jie, Xie, Ganfeng, Shi, Hang, Xue, Bingzhong, Liang, Houjie, Yu, Liqing
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268306/
https://ncbi.nlm.nih.gov/pubmed/25482557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.11.016
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