Macrophage ABHD5 promotes colorectal cancer growth by suppressing spermidine production by SRM

Metabolic reprogramming in stromal cells plays an essential role in regulating tumour growth. The metabolic activities of tumour-associated macrophages (TAMs) in colorectal cancer (CRC) are incompletely characterized. Here, we identify TAM-derived factors and their roles in the development of CRC. W...

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Udgivet i:Nat Commun
Main Authors: Miao, Hongming, Ou, Juanjuan, Peng, Yuan, Zhang, Xuan, Chen, Yujuan, Hao, Lijun, Xie, Ganfeng, Wang, Zhe, Pang, Xueli, Ruan, Zhihua, Li, Jianjun, Yu, Liqing, Xue, Bingzhong, Shi, Hang, Shi, Chunmeng, Liang, Houjie
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4873969/
https://ncbi.nlm.nih.gov/pubmed/27189574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11716
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