Muscle-Specific Deletion of Comparative Gene Identification-58 (CGI-58) Causes Muscle Steatosis but Improves Insulin Sensitivity in Male Mice

Intramyocellular accumulation of lipids is often associated with insulin resistance. Deficiency of comparative gene identification-58 (CGI-58) causes cytosolic deposition of triglyceride (TG)-rich lipid droplets in most cell types, including muscle due to defective TG hydrolysis. It was unclear, how...

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Detalhes bibliográficos
Publicado no:Endocrinology
Main Authors: Xie, Ping, Kadegowda, Anil K. G., Ma, Yinyan, Guo, Feng, Han, Xianlin, Wang, Miao, Groban, Leanne, Xue, Bingzhong, Shi, Hang, Li, Huihua, Yu, Liqing
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2015
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4398773/
https://ncbi.nlm.nih.gov/pubmed/25751639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2014-1892
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