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CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance
Mutations of Comparative Gene Identification-58 (CGI-58) in humans cause triglyceride (TG) accumulation in multiple tissues. Mice genetically lacking CGI-58 die shortly after birth due to a skin barrier defect. To study the role of CGI-58 in integrated lipid and energy metabolism, we utilized antise...
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| Autores principales: | , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The American Society for Biochemistry and Molecular Biology
2010
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952571/ https://ncbi.nlm.nih.gov/pubmed/20802159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M010256 |
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