CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance

Mutations of Comparative Gene Identification-58 (CGI-58) in humans cause triglyceride (TG) accumulation in multiple tissues. Mice genetically lacking CGI-58 die shortly after birth due to a skin barrier defect. To study the role of CGI-58 in integrated lipid and energy metabolism, we utilized antise...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Brown, J. Mark, Betters, Jenna L., Lord, Caleb, Ma, Yinyan, Han, Xianlin, Yang, Kui, Alger, Heather M., Melchior, John, Sawyer, Janet, Shah, Ramesh, Wilson, Martha D., Liu, Xiuli, Graham, Mark J., Lee, Richard, Crooke, Rosanne, Shulman, Gerald I., Xue, Bingzhong, Shi, Hang, Yu, Liqing
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2010
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952571/
https://ncbi.nlm.nih.gov/pubmed/20802159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M010256
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares