CGI-58/ABHD5-Derived Signaling Lipids Regulate Systemic Inflammation and Insulin Action

Mutations of comparative gene identification 58 (CGI-58) in humans cause Chanarin-Dorfman syndrome, a rare autosomal recessive disease in which excess triacylglycerol (TAG) accumulates in multiple tissues. CGI-58 recently has been ascribed two distinct biochemical activities, including coactivation...

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Detalhes bibliográficos
Main Authors: Lord, Caleb C., Betters, Jenna L., Ivanova, Pavlina T., Milne, Stephen B., Myers, David S., Madenspacher, Jennifer, Thomas, Gwynneth, Chung, Soonkyu, Liu, Mingxia, Davis, Matthew A., Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Parks, John S., Brasaemle, Dawn L., Fessler, Michael B., Brown, H. Alex, Brown, J. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2012
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266405/
https://ncbi.nlm.nih.gov/pubmed/22228714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0994
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