CGI-58/ABHD5-Derived Signaling Lipids Regulate Systemic Inflammation and Insulin Action

Mutations of comparative gene identification 58 (CGI-58) in humans cause Chanarin-Dorfman syndrome, a rare autosomal recessive disease in which excess triacylglycerol (TAG) accumulates in multiple tissues. CGI-58 recently has been ascribed two distinct biochemical activities, including coactivation...

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Autores principales: Lord, Caleb C., Betters, Jenna L., Ivanova, Pavlina T., Milne, Stephen B., Myers, David S., Madenspacher, Jennifer, Thomas, Gwynneth, Chung, Soonkyu, Liu, Mingxia, Davis, Matthew A., Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Parks, John S., Brasaemle, Dawn L., Fessler, Michael B., Brown, H. Alex, Brown, J. Mark
Formato: Artigo
Lenguaje:Inglês
Publicado: American Diabetes Association 2012
Materias:
Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266405/
https://ncbi.nlm.nih.gov/pubmed/22228714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-0994
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