CGI-58/ABHD5 is a coenzyme A-dependent lysophosphatidic acid acyltransferase

Mutations in human CGI-58/ABHD5 cause Chanarin-Dorfman syndrome (CDS), characterized by excessive storage of triacylglycerol in tissues. CGI-58 is an α/β-hydrolase fold enzyme expressed in all vertebrates. The carboxyl terminus includes a highly conserved consensus sequence (HXXXXD) for acyltransfer...

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Detalhes bibliográficos
Main Authors: Montero-Moran, Gabriela, Caviglia, Jorge M., McMahon, Derek, Rothenberg, Alexis, Subramanian, Vidya, Xu, Zhi, Lara-Gonzalez, Samuel, Storch, Judith, Carman, George M., Brasaemle, Dawn L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842141/
https://ncbi.nlm.nih.gov/pubmed/19801371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M001917
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